What Happens When You Stop Taking Mounjaro or Ozempic?

If you have been looking for new ways to move forward in your weight loss efforts, you have probably heard of incredine mimic drugs such as Mounjaro, Ozempic, Rybelsus, Wogovy and Zepbound. Many people have reported a dramatic weight loss when taking this type of medicines.

But what happens when you arrest taking Mimetic incretin for weight loss? Gupres weight after quitting smoking, or do you have to take them to maintain your results?

Short answer: When you stop taking mimetics incredin, you are likely to recover most of the weight you lost.

That can be discouraging when you consider the disadvantages of long -term use. To start, there is the cost, both Mounjaro and Ozímpico Have a list price of approximately $ 1,000 for one month supply. Pocket costs will vary according to their insurance plan, but they can quickly add, especially if you have to take into account your monthly budget forever.

These medications are also relatively new in the scene, which means that their long -term effects may not be completely understood. It is important to weigh all potential risks and rewards before deciding whether incredine mimnetics are suitable for you. And, of course, you should always talk to your doctor before starting (or stop!) Any medication.

If you are considering mimetic or family incredine to lose weight, this is what you need to know.

How do Mounjaro and Ozempic work?

Mounjaro, Zepbound, Ozempic, Rybelsus and Wogovy Work Mimicking Mimicking Metabolic hormones called incretins. Therefore, these medications are called incredine mimetics.

This hormonal imitation improves the body’s ability to maintain healthy levels of blood sugar. It also helps reduce appetite and food intake causing you to feel full faster and for a longer eating. As a result, many people experience weight loss as a side effect.

While all these drugs work relatively similar, there are some key differences when it comes to their planned action and use mechanisms.

SEMAGLUTED ACTION MECHANISM

These three medications are manufactured by Novo Nordisk and contain the same active ingredient, semaglutide. Semaglutida imitates the Péptide-1 hormone (LPG-1) glucagon typeIt helps promote insulin production, slow digestion and suppress appetite.

Ozímpico (injectable) and Rybelsus (pill form) are both approved by the FDA as first -line treatments for type 2 diabetes. However, doctors sometimes recipe these medications of label – That is, not as indicated – for weight loss.

Wegovy, on the other hand, is an injectable version approved by the FDA of Semaglutide formulated Specifically for weight control. It is intended for adults with overweight obesity or adults with at least one health -related health condition.

Tirzepatide Action Mechanism

The active ingredient in both Mounjaro and Zepbound is Tirzepatide. Like the semaglutida, the pullzepatide imitates the GLP-1 hormone and increases insulin sensitivity. But the mechanism of tirzepatido action also imitates the hormone of the gastric inhibitory peptide (GIP), which helps promote insulin secretion and regulate appetite and satiety.

“There have been studies that show that the tirzepatid I Ali, MDBariatric surgeon and medical director of Memorialcare Surgical Weight Pends Center in Orange Coast Medical Center in Fountain Valley, CA. “This has been attributed to affecting two receptors instead of one.”

Mounjaro and Zepbound, which are administered through injections once a week, are manufactured by Eli Lilly. Mounjaro is approved by the FDA as a Diabetes Medicationwhile Zepbound is Approved for weight control in adults with obesity or overweight adults with at least one health condition related to weight. (Does it sound familiar?)

Like Ozempic and Rybelsus, Mounjaro can be prescribed out of label to lose weight.

What happens when you stop taking GLP-1 medications to lose weight?

Incretin mimetics can help with weight control while taking them. But when you stop taking these drugs, your metabolic function return to its state prior to medication, and the number on the scale will probably do the same.

Here are some common side effects to stop Mounjaro, Ozempic and the like:

1. Your appetite will return

“[Incretin mimetics’] The main effect for weight loss is to suppress appetite and delay the emptying of the stomach, ”says Ali. “Once the medication stops, the appetite returns to its previous state and the stomach resumes to empty at normal speed. These processes can lead to a person who wants to eat more. ”

2. It is likely that you recover much of the weight you lost

Once your appetite returns to its peak, you must closely monitor your calorie consumption. “If the patient is not careful, he can start recovering weight,” says Ali.

A clinical trial found that, a year after stopping the incredine mimetics, the participants had recovered an average of Two thirds of weight They had originally lost. Their cardiomethabolic improvements also returned to the baseline.

3. Your blood sugar can increase

When you stop taking incretin mimics, says Ali, insulin secretion returns to its previous state and can notice an increase in its blood glucose levels. In Recent study reviewed by peersThe researchers divided participants into four groups. Three groups took a variable dose, while the fourth group received the Drug Drug Drug of Diabetes Type 2.

A year later, the three Tirzepatida groups had greater improvements in blood glucose levels than the diculaglutide group. However, two months after stopping the treatment, the four groups had re -elected blood glucose levels, and the pullzepatida groups were already experiencing a bounce weight gain.

The study authors concluded that their findings “suggest a need for continuous prescription or careful monitoring when stopping.”

Can you stop taking Mounjaro and Ozempic?

Given the extent to which long -term medications such as semaglutido and tirzepatido affect the body, it is not recommended to leave the cold turkey without the guide of a doctor. That said, there is no convincing evidence that interrupting its use causes serious symptoms of abstinence.

There is However, a growing research body suggests that many people experience a “fast bouncing“In blood glucose levels and weight gain after stopping incredine mimetics. These effects” are not considered withdrawal symptoms, but the return of the patient’s previous physiology, “says Ali.

Preserve weight loss after leaving incredine mimetics

Once you have achieved your weight loss objectives, it may be possible to stop taking semaglutida and tirzepatide without recovering much weight. But it must be prepared to use the following lifestyle strategies:

“If a patient can make significant changes in the long -term diet and lifestyle, then he has a better opportunity to keep the weight when medications stop,” says Ali.

As always, it is important to remember that you should always consult a medical care provider before stopping and restarting Mounjaro, Ozempic or any other medicine.

Could you consider taking weight weight medications?

Incretin mimetics may be receiving a lot of advertising, but it is important lose some stubborn pounds.

“These medications are designed for patients classified as obese with a body mass index greater than 30 or more than 27 with other comorbid conditions,” says Ali.

Even for those who meet clinical criteria, a weight loss medication is not a substitute for a balanced diet and regular exercise. Eating Dense foods in nutrients It is still the best way to obtain vitamins, minerals, fiberand Antioxidants You need. And a weight loss medication cannot resist exercise when it comes to improving strength, aerobic capacity, Heart healthBone health, and more.

How long are the GLP-1 drugs in your system?

According to food and medicines administration, the Tirzepatide half -life It’s about five days. That means that when you stop taking these drugs, the drug can take about a month to completely disappear from your body.

He half -life of semaglutida There are about seven days, so when you stop taking these drugs, you can remain in your system for approximately five weeks after the last dose.

However, to maintain their effectiveness, semaglutidas and tirzepatides are prescribed for weekly use, and are intended to be used indefinitely. “Obesity is considered as a Chronic diseasesuch as diabetes or hypertension, so patients may need to be in these long -term medications, ”says Ali.